Newcastle vs Manchester City predictions: the Toon’s toughest test & more related news here

After City scored in double figures in their FA Cup victory over Exeter, Pep Guardiola’s men travel to Tyneside confident of further cup success.

Best bets for Newcastle United vs Manchester City

• Man City will win with odds of 2.15 withBet
• Man City (1st goal) odds 1.77 withBet
• Antoine Semenyo Anytime Goalscorer with odds 2.70 withBet

Our analysis: state of form of both teams

• Score Prediction – Newcastle 1-2 Manchester City
• Goalscorer prediction – Newcastle: Wissa – Man City: Semenyo, Haaland

The Magpies come into this match after a demanding FA Cup third round tie against Bournemouth, which required extra time and a penalty shoot-out to resolve. Eddie Howe’s men may suffer the effects of that 120-minute fight. Considering the fatigue factor against champions, smart bettors could use a Bet Promo Code to back the fresher visitors and take advantage of Newcastle’s tired legs. This is because key players such as Nick Woltemade, Harvey Barnes and Sandro Tonali played the entire match.

Newcastle’s overall form has improved of late as they have won their last three Premier League games. They have not lost at St James’ Park since September, and their home fans continue to be the basis of their success. Howe faces fresh concern over the fitness of Tino Livramento, who was forced to retire with a knock.

By contrast, City enjoyed a much quieter weekend. Pep Guardiola fielded a very strong starting line-up to take on League One-chasing Exeter City. They easily dominated the Greeks 10-1 at the Etihad Stadium, conceding a consolation goal in added time.

City have drawn their last three EPL games, a run that has frustrated Guardiola. His selection of a full squad this weekend highlighted his desire to see them regain some form and gain momentum.

Probable lineups for Newcastle vs Manchester City

Expected Newcastle United lineup: Ramsdale, Hall, Thiaw, Botman, Miley; Tonalí, Guimaraes; Gordon, Barnes, Woltemade, Wissa

Expected Manchester City lineup: Trafford, O’Reilly, Khusanov, Alleyne, Nunes, González, Cherki, Foden, Reijnders, Semenyo, Haaland

City seeks a vital advantage in the first leg

Although the Magpies have won 11 of their last 13 home games in all competitions, Pep’s men are likely to get the job done. The combination of Newcastle’s exhaustion and their growing injury list presents a significant challenge.

On the contrary, Guardiola was able to make three changes at half-time against Exeter. Erling Haaland played only the first half before being replaced by Mukasa. Meanwhile, Antoine Semenyo played just over an hour and should be fit to play on Wednesday.

Furthermore, the Magpies have not kept a clean sheet in their last five meetings with City. They have also conceded six goals in their last two home games, which will worry Eddie Howe.

That is why comparing probabilities in the best betting sites and backing City to win at 46.51% odds seems like a smart bet. That’s why betting on City to win with a probability of 46.51% seems like a smart bet.

• Newcastle vs Manchester City Bet 1: Man City will win at odds of 2.15 with Bet

A good start is expected from the visitors

Manchester City’s recent record against the Magpies and their recent form against other EPL teams suggest they are the first to find the net. They have done so in eight of their last ten competitive meetings with Newcastle and seven in their last eight games in all competitions.

Although Newcastle will have home advantage, their FA Cup exploits at the weekend have probably worn them down. City easily overcame their League One rivals, so they will be fresher and have the luxury of rotating players.

City have scored first in 80% of their last ten games against Newcastle and look very likely to do so again this Wednesday. However, betting markets suggest that the visitors only have a 56.50% chance of opening the scoring. This is underrated considering City’s weekend goal fest and fresh concerns over Newcastle’s fitness.

• Newcastle vs Manchester City Bet 2: Man City (1st goal) at odds 1.77 with Bet

Semenyo’s courage to achieve consecutive matches

With 13 goals in 20 appearances for AFC Bournemouth this season, Antoine Semenyo is in top form. It is not surprising that his figures caught the attention of Manchester City, who secured his signing by activating his termination clause with the Cherries.

Semenyo made an immediate impact on his City debut. He played the first 64 minutes of City’s 10–1 victory over Exeter, registering a goal and an assist.

However, betting markets suggest he only has a 37.04% chance of scoring at St James’ Park on Wednesday. Semenyo’s performance against Exeter means Guardiola has a difficult task when deciding whether to start Semenyo or Jeremy Doku. Semenyo has recorded a 71.43% success rate in goal contributions so far in 2025/26. Backing him to score almost half that percentage is the value of our trio of Newcastle vs Man City predictions.

• Newcastle vs Manchester City Bet 3: Antoine Semenyo Goalscorer at any time at odds 2.70 with Bet

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